BEROTRALSTAT: CHMP POSITIVE OPINION FOR PEDIATRIC USE


26 June 2026

CHMP issues a positive opinion on the paediatric extension of berotralstat for the treatment of hereditary angioedema

BioCryst Ireland, a Neopharmed Gentili company, announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has adopted a positive opinion recommending the extension of the indication for berotralstat for the routine prophylaxis of recurrent attacks of hereditary angioedema (HAE) in children aged 2 to less than 12 years.

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HAELLO, WE’RE HEARE: the event to raise awareness of hereditary angioedema


13 May 2026

HAELLO, WE’RE HEARE: the event to raise awareness of hereditary angioedema

Sudden swelling, intense pain, no warning. Hereditary angioedema (HAE) occurs unpredictably. Often mistaken for a simple allergy when it affects the face and hands, or for stress and gastrointestinal disorders when it involves the abdomen, these attacks conceal a much more complex reality: HAE is a rare genetic disease affecting approximately 1 in 50,000 people¹.

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Neopharmed Gentili acquires exclusive rights to Navenibart in Europe


4 May 2026

Neopharmed Gentili acquires exclusive rights to Navenibart in Europe from BioCryst Pharmaceuticals

Neopharmed Gentili S.p.A. (“Neopharmed”), a fast-growing Italian pharmaceutical company focused on high-value therapeutic solutions, today announced that it (through its Irish affiliate) has entered into an exclusive agreement with BioCryst Pharmaceuticals, Inc. for the commercialization of navenibart in Europe, an investigational treatment for hereditary angioedema (HAE).

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ENGAGING FLOW - WHERE VASCULAR INNOVATION FLOWS


23 March 2026

Neopharmed Gentili’s scientific event in Milan: experts shine a spotlight on leg health

Leg pain and heaviness, nighttime cramps, itching, and swelling: these are some of the most common symptoms of chronic venous disease (CVD), a widespread condition affecting up to 40–50% of the Italian population.

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LUPIN AGREEMENT FOR PLASIL® IN BRAZIL AND THE PHILIPPINES


18 December 2025

Neopharmed Gentili announces Exclusive Licensing Agreement with Global Pharma Major Lupin

Neopharmed Gentili S.p.A. (“Neopharmed”), an Italian pharmaceutical company active in the marketing of high-value therapeutic solutions, controlled by the Del Bono Family and two leading international private equity firms, Ardian and Renaissance Partners, today announced that it has entered into an exclusive licensing agreement with global pharma major Lupin Limited (“Lupin”) for the commercialization and promotion of its leading gastroenterology brand Plasil® (metoclopramide) in Brazil and the Philippines.

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HYPNOSIS: A NEOPHARMED GENTILI’S EVENT ON INSOMNIA


13 November 2025

Without sleep there is no health: 1 in 4 Italians suffers from insomnia. Experts: “Listen to your sleep, never underestimate it”

In Italy, 1 in 4 adults suffers from sleep disorders and 10-15% from chronic insomnia, but the problem is often underestimated or treated superficially. Yet, sleep deprivation alters nervous system functions, weakens immune defences, compromises metabolic and cardiovascular health, and worsens mood, concentration and social relationships.

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NEOPHARMED GENTILI SUPPORTS SPORT AS A TOOL FOR INCLUSION AND FREEDOM


7 October 2025

Neopharmed Gentili supports sport as a tool for inclusion and freedom

Neopharmed Gentili has always supported sport as a tool for inclusion, growth, and freedom. This was the theme of the meeting “Beyond barriers. Sport and inclusion” held on October 9, 2025, at the Circolo degli Esteri in Rome, promoted by Formiche in collaboration with art4sport and SuperJob.

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NEOPHARMED GENTILI COMPLETES THE ACQUISITION OF ORLADEYO®


1 October 2025

Neopharmed Gentili Completes Acquisition of European ORLADEYO® Business from BioCryst Pharmaceuticals

Neopharmed Gentili S.p.A. (“Neopharmed”), a fast-growing Italian pharmaceutical company focused on high-value therapeutic solutions, today announced the successful closing of its acquisition of the European commercial operations for ORLADEYO® (berotralstat), a first-in-class oral treatment for hereditary angioedema (HAE), from BioCryst Pharmaceuticals, Inc.

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A RESPONSIBLE AND SOLID COMMITMENT TO OUR PEOPLE, THE ENVIRONMENT AND THE COMMUNITY


16 July 2025

Neopharmed Gentili strengthens its ESG commitment: people at the centre, active support for social inclusion, animals and environmental protection

In 2025, Neopharmed Gentili renews and expands its ESG (Environmental, Social, and Governance) commitment through concrete initiatives that reflect a corporate culture guided by the centrality of health, both human and animal, by the values of solidarity and inclusion, and by responsibility toward the community in which it operates.

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NEOPHARMED GENTILI ACQUIRES THE EUROPEAN ORLADEYO® BUSINESS


27 June 2025

Neopharmed Gentili acquires the European ORLADEYO® Business from BioCryst Pharmaceuticals

Milan, 27th June 2025 – Neopharmed Gentili (“Neopharmed”), an Italian pharmaceutical company active in the marketing of high-value therapeutic solutions, controlled by the Del Bono Family and two leading international private equity firms, Ardian and Renaissance Partners, announces the acquisition of the European ORLADEYO® (berotralstat) business from BioCryst Pharmaceuticals.

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NEOPHARMED GENTILI SUPPORTING CHILDREN WITH DISABILITIES


26 May 2025

Concerts of Hope: a celebration of music, inclusion, and togetherness

Neopharmed Gentili and Michael Page, as partners of the employment inclusion platform Super Job, promoted the “Concerts of Hope” initiative. The format, created by Musica su Roma, brought ten children with disabilities to the stage of Teatro dei Ginnasi in Rome to experience an afternoon of growth, sharing and creativity.

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Italian pharma firms, driving force of the national economy


17 March 2025

FAB13: the historic Made in Italy pharmaceutical companies confirm themselves as the driving force of the national economy

The latest Edison Foundation Report dedicated to the FAB13, the historic multinationals, with Italian capital, of Made in Italy pharmaceuticals, part of Farmindustria, was presented Monday 17th at the Edison Foundation. In a dialogue between Professor Marco Fortis, Vice President of the Edison Foundation, and Doctor Sebastiano Barisoni, Executive Deputy Director of Radio24, the results obtained by the Italian pharmaceutical industry in the last 20 years were analyzed in terms of growth in production, employment, research and development, innovation and exports.

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Neopharmed Gentili S.p.A. places an amount of €100 million of Senior Secured Notes


14 February 2025

Neopharmed Gentili announces the private placement of €100.0 million Senior Secured Notes due 2030

Neopharmed Gentili S.p.A., a joint stock company (società per azioni) incorporated under the laws of Italy (the “Issuer” or “Neopharmed”), has successfully priced €100.0 million of Senior Secured Notes due 2030 (the “New Notes”), in a tap issuance of the high-yield bond issued on April 8, 2024 (the “Tap Issuance”). The issuance and settlement of the New Notes is expected to occur on February 27, 2025, subject to customary closing conditions.

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NEOPHARMED GENTILI ACQUIRES METOCLOPRAMIDE PRODUCT


4 February 2025

Neopharmed Gentili executed agreement to acquire the metoclopramide product portfolio to strengthen its gastrointestinal division

Neopharmed Gentili, an Italian pharmaceutical company controlled by Ardian and NB Renaissance in partnership with the Del Bono family, which has historic roots in its territory and is pursuing international growth, announced that it has entered into an agreement with Sanofi for the acquisition of the rights in Italy and 14 other countries internationally to the Plasil® and Primperan® brands. Metoclopramide products are indicated in the prevention of nausea and vomiting.

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ERECTILE DYSFUNCTION: RAISING AWARENESS


28 September 2024

Erectile dysfunction: raising awareness of the issue and patient-friendly therapeutic solutions aligned with male sexuality

Awareness about the issue of erectile dysfunction (ED) continues to grow within the male population, alongside the availability of new therapeutic formulations that simplify care, allowing us to fully satisfy the needs of patients. Among them is sildenafil, the first phosphodiesterase inhibitor to have been developed and a treatment that is at the forefront of combating DE, now also available in an innovative spray formulation, making it easy to use and ensuring a fast-acting and effective treatment.

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YOUNG ATHLETES SHINE AT PALALUISS SPORTS AFTERNOON


16 September 2024

Inclusion through sport: young athletes take center stage at Palaluiss sports afternoon

The annual InSport event took place today at the PalaLuiss in Rome, organized by SuperJob in collaboration with CORE, Michael Page, and Luiss University, with support of the main partner Neopharmed Gentili. 20 young people with disabilities, supported by the associations Divertitempo Onlus and Mio Fratello è Figlio Unico Onlus, participated in a range of sports activities, led by coaches and assisted by athletes from Luiss Sport.

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NEOPHARMED GENTILI ANNOUNCES CEO TRANSITION


18 July 2024

Neopharmed Gentili announces CEO transition

Milan, July 18, 2024 – Neopharmed Gentili S.p.A., a leading Italian primary care branded pharmaceutical company, backed by Ardian and NB Renaissance together with the Del Bono family, announces that CEO Eric Falcand has decided to step down from his position for personal reasons. Alessandro Del Bono, who led the company prior to Eric’s appointment and is the current Chairman of the Board, will continue leading the company until a new CEO is appointed by the Board of Directors.

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NEOPHARMED GENTILI ALONGSIDE FONDAZIONE LIBELLULA


15 April 2024

Neopharmed Gentili alongside Fondazione Libellula to promote the prevention of and fight against gender-based violence

Pharmaceutical company Neopharmed Gentili has joined the Fondazione Libellula Network, the network of companies committed to preventing and combating gender-based violence through an inclusive culture.

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NEOPHARMED GENTILI S.P.A. PLACES €750 MILLION BONDS


29 March 2024

Neopharmed Gentili S.p.A. successfully completes the placement of its €750.0 million Senior Secured Notes due 2030

Milan, March 29, 2024 – Neopharmed Gentili S.p.A., a joint stock company (società per azioni) incorporated under the laws of Italy (the “Issuer” or “Neopharmed”), has successfully completed today the placement on the high-yield bond market (the “Offering”) of €750.0 million of Senior Secured Notes, consisting of €350.0 million in aggregate principal amount of Senior Secured Fixed Rate Notes due 2030 and €400.0 million in aggregate principal amount of Senior Secured Floating Rate Notes due 2030 (collectively, the “Notes”).

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SPORTS AND DISABILITY: A WINNING COMBINATION


23 October 2023

Sports and Disability: A Winning Combination

Raising awareness and facilitating discussions on topics relating to the inclusion of disabled individuals, specifically children and adolescents, promoting sports as a means of valuing diversity. This was the objective of the “INSPORT – Includere con lo sport” event, an initiative organized at the LUISS University in Rome by SuperJob, a platform providing job opportunities, information, and support to disabled individuals. The event brought together institution representatives, experts, and Third Sector Associations (TSOs), in addition to providing an opportunity for the youth from the participating associations and LUISS Athletes to come together in a sporting event.

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Eric Falcand is the new CEO of Neopharmed Gentili


1 October 2023

Eric Falcand is the new CEO of Neopharmed Gentili

Eric Falcand is the new CEO of Neopharmed Gentili, a pharmaceutical company specialised in the commercialisation of high-value therapeutic solutions, historically rooted in Italy and rapidly expanding beyond national borders, controlled by private equity firms Ardian and NB Renaissance in partnership with the Del Bono family. Falcand succeeds Alessandro Del Bono, who will continue as Executive Chairman.

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Neopharmed Gentili donates 50,000 euros for the earthquake in Turkey


9 March 2023

Neopharmed Gentili donates 50,000 euros to the Italian Red Cross to help the people affected by the earthquake in Turkey and Syria

The pharmaceutical company Neopharmed Gentili participates with a donation of 50,000 euros in the fundraising launched by the Italian Red Cross (CRI) in favor of communities affected by the violent earthquake in Turkey and Syria. The funds will be used to support the activities of Volunteers and Red Cross operators engaged in the front line of operations to support populations who are experiencing a situation of serious difficulty.

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NB Renaissance: new partner for Neopharmed Gentili and Ardian


9 November 2022

Ardian and the Del Bono family renew their partnership in Neopharmed Gentili and welcome NB Renaissance as new partner

Ardian, a world leading private investment house, today announces its reinvestment through its latest fund in Neopharmed, together with NB Renaissance, jointly holding a majority stake with equal shares. Mediolanum Farmaceutici will maintain a significant stake in the Group.

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Neopharmed Gentili acquires the Italian Valeas


27 July 2022

Neopharmed Gentili acquires the Italian Valeas and consolidates its presence in CNS, respiratory and paediatric areas

Neopharmed Gentili, an Italian pharmaceutical company active in the marketing of high-value therapeutic solutions, controlled by Ardian in partnership with the Del Bono family, acquired 100% of Valeas, a historic Italian firm widely recognized for its leadership in the paediatric, broncho-pneumological, rhino-pneumatic and neuropsychiatric (CNS) areas.

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NEOPHARMED GENTILI DONATES MEDICINES FOR UKRAINE


22 March 2022

Neopharmed Gentili donates 100.000 packages of essential medicine to the population affected by the crisis in Ukraine

Neopharmed Gentili is supporting the fundraising and medicine collection efforts undertaken by the Milan Red Cross to help address the ongoing humanitarian and health crisis in Ukraine. The Italian pharmaceutical company is donating approximately 100,000 packages of essential medication, ranging from antibiotics to painkillers (Amoxicillin trihydrate, Ceftriaxone, and Tramadol hydrochloride), in keeping with the needs of the Ukraine Red Cross to respond to the healthcare requirements of the population hit by the conflict, amidst a situation that is made all the more critical due to the unrelenting Covid-19 pandemic.

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NEOPHARMED GENTILI ACQUIRES LORMETAZEPAM PRODUCT


1 March 2022

Neopharmed Gentili acquires Lormetazepam product portfolio to strengthen its neurology division

Milan, 1st March, 2022- Neopharmed Gentili, an Italian pharmaceutical company controlled by Ardian in partnership with the Del Bono family, which has historic roots in its territory and is pursuing international growth, announced that it has entered into an agreement with Bayer for the acquisition of the rights in Italy and Japan to the historical brands Minias® and Noctamid® (Italy) and Evamyl® (Japan). Lormetazepam products are indicated in the short-term treatment of insomnia, in particular anxiety-induced insomnia.

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NEOPHARMED GENTILI ACQUIRES MDM


31 October 2019

Neopharmed Gentili, a company backed by Ardian and the Del Bono family, acquires MDM.

Neopharmed Gentili, a leading Italian pharmaceutical company active in the marketing of high-value therapeutic solutions controlled by Ardion and the Del Bono family, acquired 100% of MDM, a pharmaceutical company based in Monza active in the distribution of pharmaceuticals, nutraceuticals and medical devices for neurology and orthopedics.

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Ardian acquires majority stake in Neopharmed Gentili


28 November 2018

The Del Bono family, founders of Mediolanum Farmaceutici, has selected Ardian as a strategic partner to reinforce its presence in Italy and support its international growth.

Mediolanum Farmaceutici, a pharmaceutical company founded by the Del Bono family and now one of the most prominent players in the Italian cardiovascular market, has selected Ardian, a world-leading private investment house, as its strategic partner to further build its presence in Italy and continue the international growth plan of its subsidiary Neopharmed Gentili.

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